Description

Overview

EnquBio is a technology-driven discovery and contract research organization (CRO) based in San Diego, providing biology-focused preclinical drug discovery services. We partner with biopharmaceutical companies to accelerate the development of innovative therapeutics across multiple disease areas. As part of our continued growth, we are seeking a highly motivated Senior Scientist to join our expanding In Vivo Pharmacology team.

The Senior Scientist, In Vivo Pharmacology will serve as a scientific leader within the group, leading complex client programs and internal initiatives, driving strategic decision-making, and mentoring junior scientists. This role requires deep expertise in rodent pharmacology, a strong experience in oncology, immunology, or other relevant disease models, and the ability to thrive in a fast-paced CRO environment. The ideal candidate will demonstrate scientific excellence, strong cross-functional leadership, problem-solving capabilities, and a highly client-focused approach.

Responsibilities

        Independently lead and oversee complex in vivo pharmacology programs, serving as the primary scientific owner from program initiation through final deliverable.

        Partner with the Group Lead and scientific directors to define study strategies, prioritize resources, and align program execution with client and business objectives.

        Drive scientific decision-making on study design, model selection, dosing strategies, and data interpretation, while exercising independent judgment on complex or ambiguous challenges.

        Serve as a primary scientific contact for clients, leading scientific discussions, presenting data, providing technical guidance, and supporting long-term partnerships 

        Support business development through proposal development, capability presentations, and scientific consultations with prospective clients. 

        Author and review study protocols, reports, and scientific summaries to ensure accuracy, clarity, and high scientific quality. 

        Oversee all phases of in vivo study execution, including protocol review, in-life procedures, data analysis, interpretation, and study report preparation.

        Anticipate, identify, and resolve complex technical and operational challenges to maintain study quality, data integrity, and project timelines.

        Provide scientific leadership, mentorship, and hands-on technical guidance to Scientists and Research Associates, elevating team capability and performance.

        Lead the development, validation, and implementation of new in vivo disease models and research capabilities to expand EnquBio’s scientific offerings.

        Collaborate closely with in vitro and ex vivo teams to design integrated study platforms and deliver cohesive translational insights.

        Contribute to internal knowledge-sharing, SOP development, and continuous improvement initiatives.

        Ensure all studies comply with IACUC requirements, applicable SOPs, and animal welfare regulations, and maintain thorough and accurate study documentation.

Requirements

Qualifications

        PhD or MD in pharmacology, immunology, biology, or a related life science discipline with 3+ years of postdoctoral or industry experience; or MS with 6+ years of relevant industry experience.

        Extensive hands-on experience with rodent models and in vivo pharmacology techniques is required.

        Strong expertise in oncology, immunology, or metabolic disease models is preferred.

        Demonstrated track record of leading complex, multi-study programs in a CRO or pharmaceutical/biotech industry environment.

        Proven ability to lead cross-functional scientific teams and manage multiple programs simultaneously with a high degree of independence.

        Strong strategic thinking and problem-solving capabilities, with the ability to navigate ambiguity and drive programs forward.

        Exceptional scientific communication skills, both written and verbal, including presenting complex data to client and internal stakeholders.

        Excellent organizational skills with a meticulous attention to detail and commitment to data integrity.

        Collaborative, proactive, and solutions-oriented mindset with a strong sense of ownership and accountability.

Physical Requirements:

This role involves working in laboratory, vivarium, and office environments. Candidates must be able to:

        Work with laboratory animals, biohazardous materials, and chemicals in compliance with applicable safety standards 

        Perform routine laboratory and in vivo study procedures, including handling biological samples and research materials 

        Wear required PPE including gloves, lab coat, respirator, and eye/face protection 

        Stand, sit, and walk for extended periods; crouch, bend, twist, and reach as needed; perform tasks involving repetitive motions 

        Routinely lift, push, or pull up to 10 lbs 

        Work under standard laboratory and vivarium environmental conditions 

        Possess visual acuity sufficient to perform detailed laboratory work and data review